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  اکتوپنتین گاباپنتین
  افرادی که از دارو های ضد افسردگی یا آرام بخش استفاده می کنند.
  گاباپنتن ممکن است باعثافزایش آزادسازی GABAاز محل های غیروزیکولی شود.
  Bastaki و همکاران در تحقیقات خود به کاهش سطح سرمی اسیدآمینه متیونین در موش­های تحت درمان با لاموتریژین پی بردند.
  این اسیدآمینه یکی از آمینواسید­های ضروری بوده و
  کاهش سطح سرمی آن منجر به بروز ناهنجاری در جنین می­شود .
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